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27 Lifetime Protection for Your Heart（第1页）

27LifetimeProteforYourHeart

&oryIamabouttotellshouldbeasfamiliarasthebackofyourhandonceyouhavereadtherestofthisbook:Anindividualwithmetabolierabilitytoweightgaihesugar-filled，-impoverisheddietoftheWesternworld。Itdoesn'tmakehimfeelgreat，butheassumeshisvariousplaiuralpartofgettingolder。Pouogather;thehenalot。Nowheacquirestheriskfactorsthatsethimapartfrommostpeoplewhodon'thaveaweightprOblem。Yes，thoseriskfactors。Let'shearthemoime:

·Iarefartoohigh。

·Bloodpressurethatisrising，everrising。

·Triglyceridelevelsthathavegoelyballistic。

·Totalcholesterolthat&#htheroof。

·HDLthat'sdowninthecellar。

·Bloodsugarthat'sghtup。

What'shere'sacethatheisheadingfordiabetes。He—orshe—isfarfromhappynosforoionorahetypicalcarbohydrate-saturatedAmeridiet。Alongtheushhisdietaryfatdowhegoversaysitshouldbe。Victory?Well，no，Thatatwon'tpreveualvisittothecardiacwardofthelocalhospital。Afterall，dietaryfatheprimarysourceoftheproblem。

Thatsnapshotofalifedepictsthelifestyleofmabeyours。Youoolstodtrolyourvulie—theriskfactorsforheartdisease。You'llknowwhythesetoolsworkonceyou'vereadthischapter。Yahearthealthplanthatispreciselytailoredtotheneedsofapersonwho'ssusceptibletoweightgain。Atkinsisthedeliveranyoursusceptibility。

WhatDidn'tHappeDid

Tenyearsago，Iusedtosmilesomeainfullyattheblastsofamebymyattackers。TheysaidIdidn'trespecttheloel。"Eatingatrolledcarbh-fatdietwasda;theysaid。"Cholesterolwouldelevatewildly。Heartattackswouldsproutlikemushroomsintherain。"

&hingstrahelastdecadeofthetwerahing。MillionsofpeopledidAtkins。Physisotighatnotonlydidtheseboldnutritiourersloseweightandfeelfiheynearlyalwaysalsoshowedimprovementsintheirblood-lipidchemistries，whiitestthefurore—aretheholygrailsofmedie。

Nodoubtmanydoctorsraisedasdisciplesofthelow-fatcreedlookedatthoseresultsandwondered:Why?HowdoesfollowingAtkinsisdoit?Whydoesn'tthosepeople'schoup?Whydotheyseemsohealthy?WhatdoestheguruoftrolledcarbohydrateeatingknowthatIdon't?

Manyofthem—becausedoctorsarquiringbuartedtolearnwhatIalreadykneverwasaseulahiddenawayiory。The"secret"hasbeeedlyfightoutintheopeninmanyoftheworld'smostrespectedmedials。Theresearchthathasmadetrolledcarbohydratenutritionsopopulartodaywastrottingalongsteadilyiffthe1970sand1980s;bythelate1990sitwasmovingatafastditispositivelygallopingnow。

&is，andyoushouldknowit。

&erEffect

Whatwearelearning—carefulreaderswillnotbesurprisedisthattheriskfactorsforheartdiseaseclustertogether。Averypromierisfoundamo。AlittleoveradeanKaplan，MD，oftheUyofTexas'sSouthwesternMediter，dubbedfourriskfactorsthe"DeadlyQuartet;'Thesefour—upper-bodyobesity，gluthtriglyceridelevelsaension—werecesofasicausewasouroldfriend，hyperinsulinism。

Kaplanmadeadiagramtomakethisrelationshipclear。

&ension

Glucose

Intoleransuliriglyceridemia

Uupper-BodyObesity

Kaplanhadthegoodseicetheobvious。Theses，hereasoned，osubjectswithhighinsulinlevels，aothesameperson。Thirty-ninemillioheUesareobese（tweoveridealbodyweight），andfiftymillionpeoplearehyperteheobese，hypertensioimesmoreongtheriglyceridelevelsaretwiohanamongtheheassoisevenstrongerifoswithupper-bodyobesity。Themiddle-agedman'spauometabolicfactorsthatputhimatriskforaheartattack。

IfyoustiroioeRoi，MD，ameditistattheUyofMia。Hewrites:"Ithasbeebythefifthdecadeoflife，eighty-fivepertofdiabetidividualsarehypertensiveaypertofobesesubjectshaveabnlucosetolerandarehypertensive，andsixty-seveofhypertesarebothdiabetidobese。"

That'saprettyawe-inspiriely—aterrcluster!Doyouseeyourselfthere?Ifyoustandinohepicture，theoodthat—barringanutritionalge—you'lleventuallyoccupythe>

Kaplan'sinsightabouttheDeadlyQuartetender，asmuthoughtaboutinsulinis，eraldReaven，MD，ofStanfordUy。Inhisstudyofinsulin，hehasbeenpursuingtheebetweenhyperinsulinismandcardiovascularriskfactorswithiigablezealforoverthirtyyearsnow。OhepuzzlethatReavehathypertension—whioseriousmedicaltheoristhaseverquestionedasariskfactorforbothstrokeadisease—isiedtohyperinsulinism。In1989，inamajorarticletitled"HypertensionasaDiseaseofCarbohydrateandLipoproteiabolism;'hewrote，"Patientswithuensiooberesistanttoinsulin-stimulatedglucoseuptakeahhyperinsulinemidhypertriglyceridemietrae:Ifyouhavehighbloodpressure，youprobablyalsohavehighinsulinandtriglyceridelevels。

Iedagofriskfactorsforaryarterydisease，allofwhichwereassociatedwithhighinsulinlevelsandinsuliaheseiension，hightriglyceridelevelsanddecreasedHDLcholesterolthekindofcholesterolthathasbeenfouprotective。ReavenhasdubbedthisofriskfadromeX，andtheuck。Medicalarticlesrefertothesyndrome，andpopularhealthbooksdiscussit。It'sabuzzwordnow，asimplicitmessageisbecarefulofexcesscarbohydrateintake，Ilybehappyaboutthat。

TriglydHDL

Meanwhile，respondinginparttentmessageofSyndromeX，medicalresearchhasmovedbeyoedpredictivepoweroftotalcholesterolasanindicatorofillattaystistsnhtriglycerides，highLDL（badcholesterol）andlowHDL（goodcholesterol）asfarmorepotemindicators。AseriesoutofGermanyintheearly1990simenwhohadthebinationlydlowHDLweresixtimesmorelikelytohaveheartattameepropensities。